In this month’s issue of the JDR there are some interesting investigations that should be of interest to the dental research community. In particular, three investigations are published citing oral health disparities amongst various populations such as in elderly Europeans by Listl (http://jdr.sagepub.com/content/90/6/717.full.pdf+html ), in the USA amongst those with economic challenges by Bernabe and Marcenes ( http://jdr.sagepub.com/content/90/6/724.full.pdf+html ), and in patients exhibiting periodontitis and chronic kidney disease patients by Ioannidou and Swede ( http://jdr.sagepub.com/content/90/6/730.full.pdf+html). The better understanding of these disparities are discussed in an excellent perspective article written by Georgios Tsakos from the University College London ( http://jdr.sagepub.com/content/90/6/689.full.pdf+html ). In the biological section and cover highlight of this June issue Ken Hargreaves’ group nicely demonstrates how trigeminal neurons are capable to detect pathogenic bacterial components leading to sensitization of TRPV1. These findings might help explain how pain due to inflammation is associated with bacterial infections (http://jdr.sagepub.com/content/90/6/759.full.pdf+html ).